Российские ученые открыли, что сперматозоиды передают пространственную организацию ДНК

Опубликовано: 21.12.2019
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# Российские ученые открыли, что сперматозоиды передают пространственную организацию ДНК

!https://reprobank.ru/content/news/4a4c68b0948aaa1646c690103deda38f.png

Исследователи из Института цитологии и генетики СО РАН разработали метод для изучения пространственной структуры генома сперматозоидов мыши.

Используя технологию **Hi-C**, ученые определили, как различные части хроматина взаимодействуют друг с другом. Они обнаружили, что геном сперматозоидов организован схожим образом с другими клетками. Это открытие указывает на то, что сперматозоиды могут передавать не только генетическую информацию, но и **трехмерную структуру** ДНК.

Ранее считалось, что структура ДНК в ядре клеток хаотична. Однако последние открытия показали, что ДНК организована в сложные трехмерные структуры.

Исследования различных клеток, включая клетки мозга и кожи, показали сходную организацию ДНК. Несмотря на меньшее ядро сперматозоидов, их ДНК также организована в «домены». В сперматозоидах ДНК связана с другими белками, что придает ей уникальную структуру. Новосибирские ученые планируют углубить изучение организации ДНК в мужских половых клетках.

**На фото: изображение структуры ДНК в клетках сперматозоидов, показывающее её трехмерную организацию.**

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Ирина Васильева

Ирина Васильева

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